SC 221409, Cdk2 inhibitor (ab145053)
Key features and details
- Potent, selective, ATP-competitive Cdk2 inhibitor
- CAS Number: 222035-13-4
- Purity: > 97%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
SC 221409, Cdk2 inhibitor -
Description
Potent, selective, ATP-competitive Cdk2 inhibitor -
Biological description
Potent, selective, ATP-competitive Cdk2 inhibitor (IC50 = 60 nM). Cell-permeable.
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Purity
> 97% -
CAS Number
222035-13-4 -
Chemical structure
Properties
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Chemical name
4-[2-(5-Bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazinyl]benzenesulfonamide -
Molecular weight
395.23 -
Molecular formula
C14H11BrN4O3S -
Storage instructions
Store at -20°C (desiccating conditions). -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
NS(=O)(=O)c1ccc(cc1)N\N=C2\c3cc(Br)ccc3NC2=O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (1)
ab145053 has been referenced in 1 publication.
- DeVeale B et al. G1/S restriction point coordinates phasic gene expression and cell differentiation. Nat Commun 13:3696 (2022). PubMed: 35760790