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Overview
Product name
Anti-SCP1 antibody
See all SCP1 products (3) ...
Description
Rabbit polyclonal to SCP1
Tested applications
ICC/IF, ICCmore details
Cross reactivity
Reacts with
Mouse, Rat, Human, Pig
Immunogen
Synthetic peptide (Human) (C terminal).
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: Tris citrate/phosphate. pH 7-8
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Chromosome Structure >> Scaffold Proteins
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- SCP1 antibody (ab15087)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab15087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ICC/IF
ICC/IF: 1/300 - 1/750.ICC/IF: 1/300 - 1/750.
ICC: Use at an assay dependent concentration.
Application notes
Is unsuitable for or IHC-P.
Target
Function
Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
Tissue specificity
Testis.
Domain
Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.
Cellular localization
Nucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.
Target information above from: UniProt accessionQ15431
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Cancer/testis antigen 8 antibody
- CT8 antibody
- HOM TES 14 antibody
see all
Database links
- Entrez Gene: 6847 Human
- Entrez Gene: 20957 Mouse
- Entrez Gene: 25276 Rat
- Omim: 602162 Human
- SwissProt: Q15431 Human
- SwissProt: Q62209 Mouse
- SwissProt: Q03410 Rat
- Unigene: 112743 Human
see all
Anti-SCP1 antibody images:
- SCP1 antibody (ab15087)
SCP1 labeled in mouse pachytene preparation (red), using ab15087. CDK2 staining, near teleomeres, is also present (green).
References for Anti-SCP1 antibody (ab15087)
This product has been referenced in:
- Lee J & Hirano T RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis. J Cell Biol 192:263-76 (2011). ICC/IF; Mouse.Read more (PubMed: 21242291) »
- Brieño-Enríquez MAet al. A new culture technique that allows in vitro meiotic prophase development of fetal human oocytes. Hum Reprod 25:74-84 (2010). ICC/IF; Human.Read more (PubMed: 19828555) »
See all 6 publications for this product
Publishing research using ab15087? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"