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Anti-SCP1 antibody (ab15090)

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Overview

Product name

Anti-SCP1 antibody
See all SCP1 products (3) ...

Description

Rabbit polyclonal to SCP1

Tested applications

IHC-Fr, IHC-P, ICC/IFmore details

Cross reactivity

Reacts with

Mouse

Immunogen

Synthetic peptide (Mouse) (C terminal).

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: Tris citrate/phosphate. pH 7-8

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

  • - SCP1 antibody (ab15090)- SCP1 antibody (ab15090) image (enlarge)

  • Immunohistochemistry (Paraffin-embedded sections) - SCP1 antibody (ab15090)Immunohistochemistry (Paraffin-embedded sections) - SCP1 antibody (ab15090) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab15090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

ICC/IF: 1/100 - 1/750.
IHC-P: 1/750.
IHC-Fr: 1/750.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.

Tissue specificity

Testis.

Domain

Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.

Cellular localization

Nucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.

Target information above from: UniProt accessionQ15431 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Cancer/testis antigen 8 antibody
  • CT8 antibody
  • HOM TES 14 antibody
  • MGC104417 antibody
  • SCP 1 antibody
  • SCP-1 antibody
  • SYCP 1 antibody
  • SYCP1 antibody
  • SYCP1_HUMAN antibody
  • synaptonemal complex protein 1 antibody
see all

Anti-SCP1 antibody images:

  - SCP1 antibody (ab15090)

- SCP1 antibody (ab15090)

SCP1 labeled in mouse pachytene preparation (red), using ab15090. CDK2 staining, near teleomeres, is also present (green).

  Immunohistochemistry (Paraffin-embedded sections) - SCP1 antibody (ab15090)

Immunohistochemistry (Paraffin-embedded sections) - SCP1 antibody (ab15090)

Paraffin embeded IHC image of Murine SCP1 in mouse ovary using ab15090 at 1:750 dilution and secondary at 1:400.

References for Anti-SCP1 antibody (ab15090)

This product has been referenced in:

  • Nicholas CRet al. Intact fetal ovarian cord formation promotes mouse oocyte survival and development. BMC Dev Biol 10:2 (2010). IHC-P; Mouse.Read more (PubMed: 20064216) »
  • Fukuda Tet al. A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes. Exp Cell Res 316:158-71 (2010).Read more (PubMed: 19686734) »

See all 8 publications for this product

Publishing research using ab15090? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"