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Overview
Product name
Anti-SCP1 antibody
See all SCP1 products (3) ...
Description
Rabbit polyclonal to SCP1
Tested applications
IHC-Fr, IHC-P, ICC/IFmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Synthetic peptide (Mouse) (C terminal).
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: Tris citrate/phosphate. pH 7-8
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Chromosome Structure >> Scaffold Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab15090 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
- 1 Image
IHC-P
ICC/IF
Five stars (1 Abreview)
Application notes
ICC/IF: 1/100 - 1/750.
IHC-P: 1/750.
IHC-Fr: 1/750.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.
Tissue specificity
Testis.
Domain
Consists of an alpha-helical stretch of 700 AA residues, flanked by N- and C-terminal globular domains. The C-terminal domain has DNA-binding capacity.
Cellular localization
Nucleus. Chromosome. In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C-terminus extends well into the lateral domain of the synaptonemal complex.
Target information above from: UniProt accessionQ15431
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Cancer/testis antigen 8 antibody
- CT8 antibody
- HOM TES 14 antibody
see all
Database links
- Entrez Gene: 20957 Mouse
- SwissProt: Q62209 Mouse
- Unigene: 243849 Mouse
Anti-SCP1 antibody images:
- SCP1 antibody (ab15090)
SCP1 labeled in mouse pachytene preparation (red), using ab15090. CDK2 staining, near teleomeres, is also present (green).
Immunohistochemistry (Paraffin-embedded sections) - SCP1 antibody (ab15090)
Paraffin embeded IHC image of Murine SCP1 in mouse ovary using ab15090 at 1:750 dilution and secondary at 1:400.
References for Anti-SCP1 antibody (ab15090)
This product has been referenced in:
- Nicholas CRet al. Intact fetal ovarian cord formation promotes mouse oocyte survival and development. BMC Dev Biol 10:2 (2010). IHC-P; Mouse.Read more (PubMed: 20064216) »
- Fukuda Tet al. A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes. Exp Cell Res 316:158-71 (2010).Read more (PubMed: 19686734) »
See all 8 publications for this product
Publishing research using ab15090? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"