SDF1 alpha protein (Active) (ab79959)
Our Abpromise guarantee covers the use of ab79959 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|SDS-PAGE||SDS-PAGE: Use at an assay dependent dilution.|
- C-X-C motif chemokine 12Chemokine (C X C motif) ligand 12Chemokine (CXC motif) ligand 12
- Chemokine C X C motif ligand 12Chemokine ligand 12CXCL 12CXCL12hIRHhSDF-1Intercrine reduced in hepatomasIRHPBSFPre B cell growth stimulating factorPre-B cell growth-stimulating factorSCYB 12SCYB12SDF 1 alphaSDF 1ASDF 1BSDF-1SDF-1-alpha(3-67)SDF1SDF1_HUMANSDF1aSDF1BStromal cell derived factor 1TLSFTLSF aTLSF bTLSFaTLSFbTPAR 1TPAR1
modificationsProcessed forms SDF-1-beta(3-72) and SDF-1-alpha(3-67) are produced after secretion by proteolytic cleavage of isoforms Beta and Alpha, respectively. The N-terminal processing is probably achieved by DPP4. Isoform Alpha is first cleaved at the C-terminus to yield a SDF-1-alpha(1-67) intermediate before being processsed at the N-terminus. The C-terminal processing of isoform Alpha is reduced by binding to heparin and, probably, cell surface proteoglycans.
References for SDF1 alpha protein (Active) (ab79959)
ab79959 has not yet been referenced specifically in any publications.