Overview
Product nameSDF1 beta protein (Mouse)See all SDF1 beta proteins and peptides ...
Protein descriptionRecombinant Mouse SDF1 beta; an 8.5 kDa protein containing 72 amino acid residues.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notes>98% by SDS-PAGE and HPLC analyses.
Endotoxin level is <0.1 ng per µg.
FormLyophilised:Centrifuge the vial prior to opening. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 mg/ml. (The protein may appear as a haze or film, which is difficult to see at the bottom of the vial. )
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: None
Endotoxin level is <0.1 ng per µg.
Concentration information loading...
Additional notesThe reconstituted solution can be diluted into an aqueous buffer and stored at 4°C for 1 week or –20°C for future use.
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab51940
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| Functional Studies |
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| SDS-PAGE |
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Application notesBiological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 50-100 ng/ml.
SDS-PAGE: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
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Alternative names
Chemokine (C X C motif) ligand 12Chemokine (CXC motif) ligand 12CXCL 12
CXCL12hIRHPBSFPre B cell growth stimulating factorSCYB 12SCYB12SDF 1SDF 1 betaSDF 1aSDF 1bSDF1SDF1aSDF1bStromal cell derived factor 1Stromal cell derived factor 1 betaTLSFTLSF aTLSF bTLSFaTLSFbTPAR 1TPAR1
see all
RelevanceStromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).
Cellular localizationSecreted
References for SDF1 beta protein (Mouse) (ab51940)
ab51940
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
