Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Overview
Product name
Anti-SEC23 antibody
See all SEC23 products (4) ...
Description
Rabbit polyclonal to SEC23
Tested applications
WB, IPmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide (Human)
Positive control
Jurkat cell extract.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Applications
Show applications key
Our Abpromise guarantee covers the use of ab42109 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500Detects a band of approximately 89 kDa (predicted molecular weight: 86 kDa).
IP
IP: 1/350IP: 1/350
Target
Function
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Involvement in disease
Defects in SEC23A are the cause of craniolenticulosutural dysplasia (CLSD) [MIM:607812]; also known as cranio-lenticulo-sutural dysplasia. CLSD is an autosomal recessive syndrome characterized by late-closing fontanels, sutural cataracts, facial dysmorphisms and skeletal defects.
Sequence similarities
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Cellular localization
Smooth endoplasmic reticulum membrane. Golgi apparatus membrane. In the ribosome-free transitional face of the ER and associated vesicles.
Target information above from: UniProt accessionQ15436
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Protein transport protein Sec23A antibody
- SC23A_HUMAN antibody
- SEC23-related protein A antibody
- sec23a antibody
Database links
- Entrez Gene: 10484 Human
- Entrez Gene: 20334 Mouse
- SwissProt: Q15436 Human
- SwissProt: Q01405 Mouse
- Unigene: 272927 Human
References for Anti-SEC23 antibody (ab42109)
ab42109 has not yet been referenced specifically in any publications.
Publishing research using ab42109? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"