Anti-SH3BP5 antibody (ab126231)
Key features and details
- Rabbit polyclonal to SH3BP5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SH3BP5 antibody
See all SH3BP5 primary antibodies -
Description
Rabbit polyclonal to SH3BP5 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 248 of Human SH3BP5 (UniProt ID: O60239).
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Positive control
- THP1 whole cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126231 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 50 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 50 kDa. |
Target
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Function
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. -
Tissue specificity
Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate. -
Sequence similarities
Belongs to the SH3BP5 family. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 9467 Human
- Entrez Gene: 24056 Mouse
- Entrez Gene: 79566 Mouse
- Entrez Gene: 117186 Rat
- Omim: 605612 Human
- SwissProt: O60239 Human
- SwissProt: Q99LH9 Mouse
- SwissProt: Q9Z131 Mouse
see all -
Alternative names
- 3BP5_HUMAN antibody
- OTTHUMP00000208289 antibody
- OTTHUMP00000208291 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab126231 has not yet been referenced specifically in any publications.