Anti-SIGLEC15 antibody - N-terminal (ab174732)
Key features and details
- Rabbit polyclonal to SIGLEC15 - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SIGLEC15 antibody - N-terminal
See all SIGLEC15 primary antibodies -
Description
Rabbit polyclonal to SIGLEC15 - N-terminal -
Host species
Rabbit -
Specificity
ab174732 is predicted to not cross-react with other SIGLEC family members. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human SIGLEC15 (N terminal). (15 amino acid peptide from near the amino terminus).
Database link: Q6ZMC9 -
Positive control
- Human kidney tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab174732 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Binds sialylated glycoproteins. -
Tissue specificity
Expressed in macrophage and/or dendritic cells of spleen and lymph nodes. -
Sequence similarities
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 284266 Human
- SwissProt: Q6ZMC9 Human
- Unigene: 287692 Human
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Alternative names
- CD33 antigen-like 3 antibody
- CD33 molecule-like 3 antibody
- CD33L3 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (2)
ab174732 has been referenced in 2 publications.
- Yang WB et al. Siglec-15 promotes progression of clear renal cell carcinoma. Chin Med J (Engl) 134:2635-2637 (2021). PubMed: 34561324
- Wang JB et al. An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer. Nat Commun 11:6352 (2020). PubMed: 33311518