Overview

  • Product nameSL 327
  • Description
    MEK inhibitor
  • Biological descriptionCentrally active, brain penetrant selective MEK1 and MEK2 inhibitor (IC50 values in in vitro assays are 0.18 and 0.22 μM, respectively).
  • Purity> 99%

Properties

    References for SL 327 (ab120082)

    This product has been referenced in:
    • Wang X  et al. Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis. J Pharmacol Exp Ther 304:172-8 (2003). Read more (PubMed: 12490588) »
    • Scherle PA  et al. Regulation of cyclooxygenase-2 induction in the mouse uterus during decidualization. An event of early pregnancy. J Biol Chem 275:37086-92 (2000). Read more (PubMed: 10969080) »
    • Selcher JC  et al. A necessity for MAP kinase activation in mammalian spatial learning. Learn Mem 6:478-90 (0). Read more (PubMed: 10541468) »

    See all 6 Publications for this product

    Product Wall

    Here are certificates of analysis for the product and lot numbers you have been assigned for your orders (PO numer xxxxx, orders xxxxx and xxxxxx).


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    SL 327 (ab120082) and Kainic acid (ab120100) are both produced at >98% purity as determined by HPLC. I am checking which lots of these products have been assigned to you and then I will send the certificate ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"