Anti-SLC16A4/MCT 5 antibody (ab180699)
Key features and details
- Rabbit polyclonal to SLC16A4/MCT 5
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-SLC16A4/MCT 5 antibody
See all SLC16A4/MCT 5 primary antibodies -
Description
Rabbit polyclonal to SLC16A4/MCT 5 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Human SLC16A4/MCT 5 aa 250-350.
Database link: O15374 -
Positive control
- WB: A-549, SW480, Mouse kidney, Mouse lung extracts.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab180699 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Predicted molecular weight: 54 kDa.
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Notes |
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WB
1/1000 - 1/2000. Predicted molecular weight: 54 kDa. |
Target
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Relevance
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. -
Cellular localization
Cell membrane; Multi-pass membrane protein. -
Database links
- Entrez Gene: 9122 Human
- Entrez Gene: 229699 Mouse
- Omim: 603878 Human
- SwissProt: O15374 Human
- SwissProt: Q8R0M8 Mouse
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Alternative names
- AW146050 antibody
- MCT4 antibody
- MCT5 antibody
see all
Images
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All lanes : Anti-SLC16A4/MCT 5 antibody (ab180699) at 1/1000 dilution
Lane 1 : A-549 cell lysate
Lane 2 : SW480 cell lysate
Lane 3 : Mouse kidney extract
Lane 4 : Mouse lung extract
Secondary
All lanes : HRP Goat Anti-Rabbit IgG
Developed using the ECL technique.
Predicted band size: 54 kDa
Exposure time: 60 secondsBlocking buffer: 3% nonfat dry milk in TBST.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab180699 has been referenced in 4 publications.
- Wang Y et al. Intratumor heterogeneity of breast cancer detected by epialleles shows association with hypoxic microenvironment. Theranostics 11:4403-4420 (2021). PubMed: 33754068
- Cai P et al. Treatment with, Resveratrol, a SIRT1 Activator, Prevents Zearalenone-Induced Lactic Acid Metabolism Disorder in Rat Sertoli Cells. Molecules 24:N/A (2019). PubMed: 31284444
- Horii N et al. High-intensity intermittent exercise training with chlorella intake accelerates exercise performance and muscle glycolytic and oxidative capacity in rats. Am J Physiol Regul Integr Comp Physiol 312:R520-R528 (2017). PubMed: 28122719
- Zeng N et al. 1a,25(OH) 2D3 Sensitive Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Ishikawa Cells. Cell Physiol Biochem 41:678-688 (2017). PubMed: 28222424