Anti-SLC5A3 antibody (ab113245)
Key features and details
- Rabbit polyclonal to SLC5A3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SLC5A3 antibody
See all SLC5A3 primary antibodies -
Description
Rabbit polyclonal to SLC5A3 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human SLC5A3 aa 221-270 (internal sequence) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P53794 -
Positive control
- Human prostate and Human uterus tissue and extracts from HUVEC cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine), 48% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab113245 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 80 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 80 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function. -
Sequence similarities
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 6526 Human
- Entrez Gene: 53881 Mouse
- Entrez Gene: 114507 Rat
- Omim: 600444 Human
- SwissProt: P53794 Human
- SwissProt: Q9JKZ2 Mouse
- Unigene: 302742 Human
- Unigene: 217354 Mouse
see all -
Alternative names
- Na(+)/myo inositol cotransporter antibody
- Na(+)/myo-inositol cotransporter antibody
- SC5A3_HUMAN antibody
see all
Images
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ab113245, at 5 µg/ml, staining SLC5A3 in formalin fixed, paraffin embedded Human prostate tissue.
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ab113245, at 5 µg/ml, staining SLC5A3 in formalin fixed, paraffin embedded Human uterus tissue.
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All lanes : Anti-SLC5A3 antibody (ab113245) at 1/500 dilution
Lane 1 : HUVEC cell extract
Lane 2 : HUVEC cell extract with synthetic peptide
Predicted band size: 80 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab113245 has been referenced in 3 publications.
- Britten JL et al. Ulipristal Acetate Mediates Decreased Proteoglycan Expression Through Regulation of Nuclear Factor of Activated T-Cells (NFAT5). Reprod Sci 26:184-197 (2019). PubMed: 30567472
- Zhang X et al. The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis. Nat Commun 8:15280 (2017). WB ; Human . PubMed: 28474680
- Van Steenbergen A et al. Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart. Sci Rep 7:41166 (2017). PubMed: 28128227