Anti-NHERF-2/SIP-1 antibody (ab96562)
Key features and details
- Rabbit polyclonal to NHERF-2/SIP-1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NHERF-2/SIP-1 antibody
See all NHERF-2/SIP-1 primary antibodies -
Description
Rabbit polyclonal to NHERF-2/SIP-1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Pig -
Immunogen
Recombinant fragment corresponding to Human NHERF-2/SIP-1 aa 82-317.
Database link: NP_004776 -
Positive control
- NT2D1 cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96562 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 37 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 37 kDa. |
Target
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Function
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. -
Tissue specificity
Widely expressed. -
Sequence similarities
Contains 2 PDZ (DHR) domains. -
Cellular localization
Endomembrane system. Nucleus. Apical cell membrane. Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. - Information by UniProt
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Database links
- Entrez Gene: 768005 Cow
- Entrez Gene: 9351 Human
- Entrez Gene: 65962 Mouse
- Entrez Gene: 100192448 Pig
- Entrez Gene: 116501 Rat
- Omim: 606553 Human
- SwissProt: Q15599 Human
- SwissProt: Q9JHL1 Mouse
see all -
Alternative names
- E3KARP antibody
- HGNC:11076 antibody
- Isoform 3 regulator 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab96562 has not yet been referenced specifically in any publications.