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Overview

  • Product nameAnti-SLUG antibody [2H5]See all SLUG primary antibodies ...
  • Description
    Mouse monoclonal [2H5] to SLUG
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment of Human SLUG expressed in E. Coli.

  • Positive controlSLUG-hIgGFc transfected HEK293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab130201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/2000. Predicted molecular weight: 29 kDa.
ELISA ELISA: 1/10000.

Target

  • FunctionTranscriptional repressor. Involved in the generation and migration of neural crest cells.
  • Tissue specificityExpressed in placenta and adult heart, pancreas, liver, kidney and skeletal muscle.
  • Involvement in diseaseDefects in SNAI2 are the cause of Waardenburg syndrome type 2D (WS2D) [MIM:608890]. WS2 is a genetically heterogeneous, autosomal dominant disorder characterized by sensorineural deafness, pigmentary disturbances, and absence of dystopia canthorum. The frequency of deafness is higher in WS2 than in WS1.
  • Sequence similaritiesBelongs to the snail C2H2-type zinc-finger protein family.
    Contains 5 C2H2-type zinc fingers.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession O43623 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        MGC10182 antibodyNeural crest transcription factor Slug antibodyProtein snail homolog 2 antibody
        Slug (chicken homolog) zinc finger protein antibodySlug homolog zinc finger protein antibodySlug zinc finger protein antibodySLUGH antibodySLUGH 1 antibodySLUGH1 antibodySNAI 2 antibodySnai2 antibodySNAI2_HUMAN antibodySnail 2 antibodySnail homolog 2 antibodySnail2 antibodyWS 2D antibodyWS2D antibodyZinc finger protein SLUG antibodyZinc finger protein SNAI2 antibody
      see all

    Anti-SLUG antibody [2H5] images

    • Western blot - Anti-SLUG antibody [2H5] (ab130201)
      Western blot - Anti-SLUG antibody [2H5] (ab130201)
      Anti-SLUG antibody [2H5] (ab130201) at 1/500 dilution + SLUG-hIgGFc transfected HEK293 cell lysate

      Predicted band size : 29 kDa

    References for Anti-SLUG antibody [2H5] (ab130201)

    ab130201 has not yet been referenced specifically in any publications.

    Publishing research using ab130201 ? Please let us know so that we can cite the reference in this datasheet

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