Overview

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • Clonality Monoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab57569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceSLURP1 (Secreted LY6/PLAUR domain containing 1) belongs to the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. SLURP1 potentiates alpha-7 nicotinic acetylcholine receptors (CHRNA7) in keratinocytes and is implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. It is a marker of late differentiation of the skin and has an antitumor activity. Mutations in the SLURP1 gene are the cause of Mal de Meleda (MDM), a rare autosomal recessive genetic disease, characterized by inflammatory palmoplantar keratoderma.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Anti neoplastic urinary protein antibody
      • ANUP antibody
      • ARS antibody
      • ARS component B antibody
      • ARS(component B) 81/S antibody
      • ArsB antibody
      • LY6LS antibody
      • Lymphocyte antigen 6 like secreted antibody
      • MDM antibody
      • Results in cobblestone changes in the skin of the palm antibody
      • Secreted Ly 6/uPAR related protein 1 antibody
      • Secreted LY6/PLAUR domain containing 1 antibody
      • Secreted Ly6/uPAR related protein 1 antibody
      • SLURP 1 antibody
      see all

    Anti-SLURP1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57569 SLURP1 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    References for Anti-SLURP1 antibody (ab57569)

    This product has been referenced in:
    • Gay M  et al. Proteomic Analysis of Polypeptides Captured from Blood during Extracorporeal Albumin Dialysis in Patients with Cholestasis and Resistant Pruritus. PLoS One 6:e21850 (2011). WB ; Human . Read more (PubMed: 21779339) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab57569.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"