FunctionMitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity.
Tissue specificityExpressed in all tissues tested with highest expression in heart and skeletal muscle.
Sequence similaritiesBelongs to the MID49/MID51 family.
Cellular localizationMitochondrion outer membrane. Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.