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Overview

  • Product nameSNAP
  • Description
    NO donor
  • Biological descriptionNO donor. Vasodilator in vitro and in vivo, that does not induce pharmacological tolerance.

    • Properties

  • Chemical nameS-Nitroso-N-acetyl-DL-penicillamin
  • Molecular Weight220.24
  • Chemical structureChemical Structure
  • Molecular formulaC7H12N2O4S
  • CAS Number67776-06-1
  • PubChem identifier5231
  • Storage instructionsStore at -20°C (desiccating conditions).
  • Solubility overviewSoluble in DMSO to 100 mM
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESCC(C)(SN=O)C(NC(=O)C)C(=O)O
  • Source

    Synthetic

  • Research Areas

    • References for SNAP (ab120014)

    This product has been referenced in:
    • Ignarro LJ  et al. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview. Circ Res 90:21-8 (2002). Read more (PubMed: 11786514) »
    • Yamamoto T & Bing RJ Nitric oxide donors. Proc Soc Exp Biol Med 225:200-6 (2000). Read more (PubMed: 11082214) »
    • Ferrero R  et al. Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: correlation with nitric oxide production. Br J Pharmacol 127:779-87 (1999). Read more (PubMed: 10401570) »
    • Shaffer JE  et al. Lack of tolerance to a 24-hour infusion of S-nitroso N-acetylpenicillamine (SNAP) in conscious rabbits. J Pharmacol Exp Ther 260:286-93 (1992). Read more (PubMed: 1731043) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"