Anti-SNAP23 antibody (ab166808)
Key features and details
- Goat polyclonal to SNAP23
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SNAP23 antibody
See all SNAP23 primary antibodies -
Description
Goat polyclonal to SNAP23 -
Host species
Goat -
Specificity
ab166808 is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1). -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide:
QIKRITDKAD
by a Cysteine residue linker, corresponding to internal sequence amino acids 183-192 of Human SNAP23 (NP_003816.2). -
Positive control
- Human placenta lysate; Human spleen tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab166808 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 23 kDa).
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IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 23 kDa). |
IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. -
Tissue specificity
Ubiquitous. Highest levels where found in placenta. -
Sequence similarities
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains. -
Cellular localization
Cell membrane. Cell membrane. Cell junction, synapse, synaptosome. Mainly localized to the plasma membrane. - Information by UniProt
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Database links
- Entrez Gene: 101141000 Gorilla
- Entrez Gene: 8773 Human
- Entrez Gene: 100174679 Orangutan
- Omim: 602534 Human
- SwissProt: O00161 Human
- Unigene: 511149 Human
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Alternative names
- HsT17016 antibody
- LS-B8340 antibody
- SNAP 23 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab166808 has been referenced in 1 publication.
- da Silva LB et al. Botulinum neurotoxin type A modulates vesicular release of glutamate from satellite glial cells. J Cell Mol Med 19:1900-9 (2015). ICC, IHC . PubMed: 25754332