Overview

  • Product nameAnti-SNAP25 antibody
    See all SNAP25 primary antibodies
  • Description
    Rabbit polyclonal to SNAP25
  • Tested applicationsWB, IHC-FoFrmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken, Cow, Xenopus laevis, Chimpanzee, Cynomolgus Monkey, Orangutan
  • Immunogen

    Synthetic peptide:

    NELEEMQRRADQLADESLEST-K

    conjugated to KLH, corresponding to N terminal amino acids 9-29 of Human SNAP25

  • Positive control
    • Cytosolic fraction of mouse brain extract; whole cell extract of the rat pheochromocytoma PC12 cell line; formalin-fixed, paraffin-embedded sections of rat cerebellum

Properties

Applications

Our Abpromise guarantee covers the use of ab51008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-FoFr
  • Application notesIHC-Fo: 1/5000.
    WB: 1/5000 - 1/10000. Predicted molecular weight: 23 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Functiont-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
    • Tissue specificityNeurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
    • Sequence similaritiesBelongs to the SNAP-25 family.
      Contains 2 t-SNARE coiled-coil homology domains.
    • Post-translational
      modifications
      Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association.
    • Cellular localizationCytoplasm > perinuclear region. Cell membrane. Cell junction > synapse > synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.
    • Information by UniProt
    • Database links
    • Alternative names
      • bA416N4.2 antibody
      • Bdr antibody
      • dJ1068F16.2 antibody
      • FLJ23079 antibody
      • HGNC:11132 antibody
      • MGC105414 antibody
      • MGC139754 antibody
      • Resistance to inhibitors of cholinesterase 4 homolog antibody
      • RIC 4 antibody
      • RIC4 antibody
      • SEC 9 antibody
      • SEC9 antibody
      • SNAP 25 antibody
      • SNAP antibody
      • SNAP-25 antibody
      • SNAP-25B antibody
      • SNAP25 antibody
      • SNP 25 antibody
      • SNP25 antibody
      • SNP25_HUMAN antibody
      • sp antibody
      • SUP antibody
      • SUP antibody
      • Super protein antibody
      • Super protein antibody
      • Synaptosomal associated 25 kDa protein antibody
      • Synaptosomal associated protein antibody
      • Synaptosomal Associated Protein 25 antibody
      • Synaptosomal associated protein 25kDa antibody
      • Synaptosomal-associated 25 kDa protein antibody
      • Synaptosomal-associated protein 25 antibody
      • Synaptosomal-associated protein, 25-KD antibody
      see all

    References for Anti-SNAP25 antibody (ab51008)

    ab51008 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab51008.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"