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Product Name
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SPARC antibody
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See all SPARC antibodies (8)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to SPARC
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Immunogen
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Synthetic peptide: TCDLDNDKYIALDEW, corresponding to amino acids 272-286 of Human SPARC.
BLAST 'TCDLDNDKYIALDEW' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cow
(Due to sequence homology)
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Specificity
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There were no cross reactivities obtained with human Osteopontin, and human Bone Sialoprotein.
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Tested applications
(see key)
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/3000.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted, extracellular space, extracellular matrix, basement membrane. Note: In or around the basement membrane.
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Research areas
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Developmental Biology >> Lineage specification >> Endoderm
Cancer >> Signal transduction >> Protein phosphorylation >> Tyrosine kinases >> Receptor tyrosine kinases
Stem Cells >> Mesenchymal Stem Cells >> Osteogenesis
Stem Cells >> Lineage Markers >> Endoderm
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Bone
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
Cardiovascular >> Angiogenesis >> Adhesion / ECM >> Extracellular Matrix
Cell Biology >> Cell Cycle >> Cell Cycle Inhibitors >> Other
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Relevance
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SPARC is a secreted protein, acidic and rich in cysteines. It is a matrix associated protein that elicits changes in cell shape, inhibits cell cycle progression, and influences the synthesis of extracellular matrix (ECM).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole Serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this SPARC antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to SPARC
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SPARC antibody - more information
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Customer reviews (feedback) regarding SPARC antibody |
Customer FAQs regarding SPARC antibody |
Protocols for SPARC antibody |
Price and availability of products related to SPARC antibody |
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SPARC antibody - related products:
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SPARC antibody - other tools:
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Contact Abcam with a Technical Enquiry about SPARC antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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