Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-EDEPLETATKEN
    • Amino acids
      328 to 339

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-SPFH2 antibody (ab36123)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • C8orf2
    • Chromosome 8 open reading frame 2
    • Endoplasmic reticulum lipid raft associated protein 2
    • Endoplasmic reticulum lipid raft-associated protein 2
    • ER lipid raft associated 2
    • ERLIN 2
    • Erlin-2
    • ERLIN2
    • ERLN2_HUMAN
    • HGNC:1356
    • MGC87072
    • NET32
    • SPFH 2
    • SPFH domain containing protein 2
    • SPFH domain family member 2
    • SPFH domain-containing protein 2
    • SPFH2
    • SPG18
    • Stomatin prohibitin flotillin HflC/K domain containing protein 2
    • Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
    see all
  • Function
    Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the band 7/mec-2 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
  • Information by UniProt

References

ab45803 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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