The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-SPFH2 antibody (ab36123)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Chromosome 8 open reading frame 2
Endoplasmic reticulum lipid raft associated protein 2
Endoplasmic reticulum lipid raft-associated protein 2
ER lipid raft associated 2
SPFH domain containing protein 2
SPFH domain family member 2
SPFH domain-containing protein 2
Stomatin prohibitin flotillin HflC/K domain containing protein 2
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
FunctionComponent of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway.
Sequence similaritiesBelongs to the band 7/mec-2 family.
Cellular localizationEndoplasmic reticulum membrane. Associated with lipid raft-like domains of the endoplasmic reticulum membrane.