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Anti-SSRP1 antibody [3E4] (ab26229)

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Overview

Product name

Anti-SSRP1 antibody [3E4]
See all SSRP1 products (4) ...

Description

Mouse monoclonal [3E4] to SSRP1

Tested applications

WB, IPmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment (Human)

Positive control

HeLa cell lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 50% Glycerol, PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

3E4

Isotype

IgG1

Light chain type

kappa

Research areas

Epigenetics and Nuclear Signaling >> Transcription >> Elongation factors
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Epigenetics and Nuclear Signaling >> Chromatin Remodeling >> FACT

  • Western blot - SSRP1 antibody [3E4] (ab26229)Western blot - SSRP1 antibody [3E4] (ab26229) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab26229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63.

Cellular localization

Nuclear

Alternative names

  • Chromatin-specific transcription elongation factor 80 kDa subunit antibody
  • Cisplatin DNA SSRP antibody
  • Facilitates chromatin remodeling 80 kDa subunit antibody
  • Facilitates chromatin transcription complex subunit SSRP1 antibody
  • FACT 80 kDa subunit antibody
  • FACT complex subunit SSRP1 antibody
  • FACT80 antibody
  • FACTp80 antibody
  • hSSRP1 antibody
  • Recombination signal sequence recognition protein 1 antibody
  • Recombination signal sequence recognition protein antibody
  • SSRP 1 antibody
  • Structure specific recognition protein 1 antibody
  • Structure-specific recognition protein 1 antibody
  • T160 antibody
see all

Database links

Anti-SSRP1 antibody [3E4] images:

  Western blot - SSRP1 antibody [3E4] (ab26229)

Western blot - SSRP1 antibody [3E4] (ab26229)

Anti-SSRP1 antibody [3E4] (ab26229) at 1 µg/ml + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab7898)
developed using the ECL technique

Predicted band size : 81 kDa

References for Anti-SSRP1 antibody [3E4] (ab26229)

This product has been referenced in:

See 1 publication for this product

Publishing research using ab26229? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"