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Products:Epigenetics and Nuclear Signaling >> Chromatin Remodeling >> FACT
Overview
Product name
SSRP1 peptide
See all SSRP1 products (2) ...
Protein description
Synthetic peptide derived from within residues 600 - 700 of Human SSRP1. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab21584 - SSRP1 antibody.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
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Protein info
Relevance
SSRP1 is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63.
Cellular localization
Nuclear
References for SSRP1 peptide (ab22404)
ab22404 has not yet been referenced specifically in any publications.
Publishing research using ab22404? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"