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Product Name
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STAT5b antibody
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See all STAT5b antibodies (11)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to STAT5b
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Immunogen
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Synthetic STAT5b peptide (Human)
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Reacts with
(species key)
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Hu, Ms
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/1000. Detects a band of approximately 96 kDa (In mouse, this protein is truncated and displays as an 80kDa band).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic and Nuclear: Translocated into the
nucleus in response to phosphorylation.
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Research areas
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Cancer >> Cancer Metabolism >> Response to hypoxia
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> STATs
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> STATs
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Relevance
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Stats (signal transducers and activators of transcription) are transcription factors that are activated by JAK family kinases. Stat1 and Stat2 are induced by IFN alpha and forn1 a heterodimer which is part of the ISGF-3 transcription factor complex. Stat3 beta appears to be activated by both EGF and IL6, but Stat3 alpha is activated by only by EGF. Stat4, predominantly expressed in testis and myeloid cells, is activated by ILl2. Stat 5 is activated by prolactin and IL3. Stat 6 participates in signaling pathways mediated by IL4.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this STAT5b antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to STAT5b
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STAT5b antibody - more information
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Customer reviews (feedback) regarding STAT5b antibody |
Customer FAQs regarding STAT5b antibody |
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