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Western blot - STAU2 antibody (ab60724)
(enlarge)
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Product Name
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STAU2 antibody
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See all STAU2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to STAU2
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Immunogen
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Recombinant fragment with tag:
LQINQMFSVQ LSLGEQTWES EGSSIKKAQQ AVANKALTES TLPKPVQKPP KSNVNNNPGS ITPTVELNGL AMKRGEPAIY RPLDPKPFP, corresponding to amino acids 2-91 of Human STAU2
BLAST 'LQINQMFSVQ LSLGEQTWES EGSSIKKAQQ AVANKALTES TLPKPVQKPP KSNVNNNPGS ITPTVELNGL AMKRGEPAIY ' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Chmp, Cow, Dog, Hrs, RMk, Orngt
(Due to sequence homology)
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution. The detection limit for recombinant tagged STAU2 is approximately 0.03ng/ml as a capture antibody.
WB: Use at a concentration of 1 - 5 µg/ml. Detects a band of approximately 53 kDa (predicted molecular weight: 63 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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IMR-32 cell lysate.
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Cellular localization
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Cytoplasm. Nucleus. Nucleus, nucleolus. Note: Shuttles between the nucleolus, nucleus and the cytoplasm.
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Research areas
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Chromatin and Nuclear Signaling >> Chromatin Binding Proteins >> DNA / RNA binding
Neuroscience >> Neurology process >> Growth and Development >> Axonal Guidance Proteins
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules
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Relevance
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STAU2 is an RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this STAU2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for STAU2 antibody images, references, products related to ab60724 and other tools.
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STAU2 antibody images:
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 Western blot - STAU2 antibody (ab60724)
STAU2 antibody (ab60724) at 1 µg/ml + IMR-32 cell lysate at 25 µg
Predicted band size : 63 kDa
Observed band size : 53 kDa (why is the actual band size different from the predicted?)
Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.
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Search PubMed (MEDLINE) for references to STAU2
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STAU2 antibody - more information
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Customer reviews (feedback) regarding STAU2 antibody |
Customer FAQs regarding STAU2 antibody |
Protocols for STAU2 antibody |
Price and availability of products related to STAU2 antibody |
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STAU2 antibody - related products:
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STAU2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about STAU2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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