Anti-STEAP4 antibody (ab113230)
Key features and details
- Rabbit polyclonal to STEAP4
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-STEAP4 antibody
See all STEAP4 primary antibodies -
Description
Rabbit polyclonal to STEAP4 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide conjugated to KLH from Human STEAP4.
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Positive control
- Human Liver and Skin tissues; HeLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS (without Mg2+, Ca2+) -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab113230 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 10 µg/ml.
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ICC/IF |
1/100 - 1/500.
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Notes |
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IHC-P
Use a concentration of 10 µg/ml. |
ICC/IF
1/100 - 1/500. |
Target
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Function
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation. -
Tissue specificity
Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages. -
Sequence similarities
Belongs to the STEAP family.
Contains 1 ferric oxidoreductase domain. -
Cellular localization
Cell membrane. Golgi apparatus membrane. - Information by UniProt
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Database links
- Entrez Gene: 79689 Human
- Omim: 611098 Human
- SwissProt: Q687X5 Human
- Unigene: 521008 Human
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Alternative names
- alpha-induced protein 9 antibody
- Metalloreductase STEAP4 antibody
- six transmembrane prostate protein 2 antibody
see all
Images
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ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.
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ab113230, at 10µg/ml, staining STEAP4 in Formalin-fixed, Paraffin-embedded Human Skin tissue by Immunohistochemistry.
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ab113230 at 1/100 dilution staining STEAP4 in HeLa cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab113230 has not yet been referenced specifically in any publications.