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Products:Signal Transduction >> Protein Trafficking >> Chaperones >> Heat Shock Proteins
Overview
Product name
Anti-STIP1 antibody
See all STIP1 products (9) ...
Description
Mouse monoclonal to STIP1
Tested applications
WB, IHC-P, IPmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-544 of Human STIP1
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Signal Transduction >> Protein Trafficking >> Chaperones >> Heat Shock Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56873 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 63 kDa.
IHC-P: Use a concentration of 5 µg/ml
IP: Use at an assay dependent concentration. (PubMed: 21470770)
Target
Function
Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
Sequence similarities
Contains 2 STI1 domains.
Contains 9 TPR repeats.
Domain
The TPR 1 repeat interacts with the C-terminal of HSC70. The TPR 4, 5 and 6 repeats (also called TPR2A domain) and TPR 7, 8 and 9 repeats (also called TPR2B domain) interact with HSP90.
Cellular localization
Cytoplasm. Nucleus.
Target information above from: UniProt accessionP31948
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Hop antibody
- Hsc70/Hsp90 organizing protein antibody
- Hsc70/Hsp90-organizing protein antibody
see all
Database links
- Entrez Gene: 10963 Human
- Omim: 605063 Human
- SwissProt: P31948 Human
- Unigene: 337295 Human
Anti-STIP1 antibody images:
IHC-P - STIP1 antibody (ab56873)
STIP1 antibody (ab56873) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human testis.
Western blot - STIP1 antibody (ab56873)
STIP1 antibody (ab56873) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-STIP1 antibody (ab56873)
This product has been referenced in:
- Walsh Net al. RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. Cancer Lett 306:180-9 (2011). WB, IHC-P, IP; Human.Read more (PubMed: 21470770) »
See 1 publication for this product
Publishing research using ab56873? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"