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Products:Signal Transduction >> Protein Trafficking >> Chaperones >> Heat Shock Proteins
Overview
Product name
Anti-STIP1 antibody
See all STIP1 products (9) ...
Description
Mouse monoclonal to STIP1
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: TKAMDVYQKA LDLDSSCKEA ADGYQRCMMA QYNRHDSPED VKRRAMADPE VQQIMSDPAM RLILEQMQKD PQALSEHLKN PVIAQKIQKL MDVGLIAIR, corresponding to amino acids 445-544 of Human STIP1
TKAMDVYQKA LDLDSSCKEA ADGYQRCMMA QYNRHDSPED VKRRAMADPE VQQIMSDPAM RLILEQMQKD PQALSEHLKN PVIAQKIQKL MDVGLIAIR
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Signal Transduction >> Protein Trafficking >> Chaperones >> Heat Shock Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56874 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
WB: Use at a concentration of 1-5 µg/ml.
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
Sequence similarities
Contains 2 STI1 domains.
Contains 9 TPR repeats.
Domain
The TPR 1 repeat interacts with the C-terminal of HSC70. The TPR 4, 5 and 6 repeats (also called TPR2A domain) and TPR 7, 8 and 9 repeats (also called TPR2B domain) interact with HSP90.
Cellular localization
Cytoplasm. Nucleus.
Target information above from: UniProt accessionP31948
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Hop antibody
- Hsc70/Hsp90 organizing protein antibody
- Hsc70/Hsp90-organizing protein antibody
see all
Database links
- Entrez Gene: 10963 Human
- Omim: 605063 Human
- SwissProt: P31948 Human
- Unigene: 337295 Human
Anti-STIP1 antibody images:
IHC-P - STIP1 antibody (ab56874)
STIP1 antibody (ab56874) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
Western blot - STIP1 antibody (ab56874)
STIP1 antibody (ab56874) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-STIP1 antibody (ab56874)
ab56874 has not yet been referenced specifically in any publications.
Publishing research using ab56874? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"