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Overview

  • Product nameSTK25 protein (Active)See all STK25 proteins and peptides ...
  • Protein descriptionRecombinant full length Human STK25 (amino acids 1-426) with a N terminal proprietary tag; MWt 76kDa inclusive of tag. (O00506, NM_006374).
  • Uniprot accessionO00506
  • Molecular weight76kDa inclusive of tags
  • Protein length426 amino acids
  • Expression hostBaculovirus infected sf9 cells

    • Properties

  • Purification notesThe purity was determined to be 90% by densitometry
  • Biological activityThe specific activity of ab125588 was determined to be 11 nmol/min/mg.
  • E.C. Number2.7.11.1
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferpH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab125588 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution.
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab157188.

    • Protein info

    • Alternative names
        C86992Serine/threonine kinase 25Serine/threonine kinase 25 (STE20 homolog, yeast)
        Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_aSerine/threonine kinase 25 (yeast)Serine/threonine protein kinase 25Serine/threonine-protein kinase 25SOK 1SOK-1SOK1Ste20 like kinaseSte20 yeast homologSte20-likeSTE20-like kinaseSte20/oxidant stress response kinase 1Sterile 20 (oxidant stress response kinase 1)Sterile 20/oxidant stress-response kinase 1STK25STK25_HUMANYeast Sps1/Ste20 related kinase 1YSK 1YSK1
      see all
  • FunctionOxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
  • Tissue specificityUbiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Golgi apparatus. Localizes to the Golgi apparatus.

    • Target information above from: UniProt accession O00506 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    STK25 protein (Active) images

    • SDS-PAGE - STK25 protein (Active) (ab125588)
      SDS-PAGE - STK25 protein (Active) (ab125588)
      SDS Page analysis of ab125588
    • Functional Studies - STK25 protein (Active) (ab125588)
      Functional Studies - STK25 protein (Active) (ab125588)
      The specific activity of ab125588 was determined to be 11 nmol/min/mg

    References for STK25 protein (Active) (ab125588)

    ab125588 has not yet been referenced specifically in any publications.

    Publishing research using ab125588 ? Please let us know so that we can cite the reference in this datasheet

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