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Products:Neuroscience >> Neurology process >> Neurogenesis
Overview
Product name
Anti-STMN2 antibody
See all STMN2 products (5) ...
Description
Goat polyclonal to STMN2
Tested applications
Cross reactivity
Reacts with
Rat, Human
Immunogen
Synthetic peptide: AKTAMAYKEK, corresponding to N terminal amino acids 2-11 of STMN2
AKTAMAYKEK
Positive control
Human Brain lysate, A431 lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Isotype
IgG
Research areas
-
Western blot - STMN2 antibody (ab21190)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab21190 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.1 - 1 µg/ml.Predicted molecular weight: 20.8 kDa.
Target
Function
Is a key regulator of neurite extension through regulation of microtubule instabilily.
Tissue specificity
Neuron specific.
Sequence similarities
Belongs to the stathmin family.
Post-translational
modifications
Sumoylated.
Cellular localization
Cytoplasm. Cytoplasm > perinuclear region. Cell projection > growth cone. Membrane. Cell projection > axon. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms.
Target information above from: UniProt accessionQ93045
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Neuronal growth associated protein antibody
- Protein SCG10 antibody
- SCG 10 antibody
see all
Database links
- Entrez Gene: 11075 Human
- Entrez Gene: 84510 Rat
- Omim: 600621 Human
- SwissProt: Q93045 Human
- SwissProt: P21818 Rat
- Unigene: 521651 Human
- Unigene: 34335 Rat
Anti-STMN2 antibody images:
Western blot - STMN2 antibody (ab21190)
Anti-STMN2 antibody (ab21190) at 1 µg/ml + Human Brain lysate (RIPA buffer, 35µg total protein per lane).
Predicted band size : 20.8 kDa
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
References for Anti-STMN2 antibody (ab21190)
This product has been referenced in:
- Davis EJet al. Intrastriatal dopamine D1 antagonism dampens neural plasticity in response to motor cortex lesion. Neuroscience 146:784-91 (2007).Read more (PubMed: 17331653) »
See 1 publication for this product
Publishing research using ab21190? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"