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Products:Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Other dsDNA viruses
Overview
Product name
Anti-SV40 T-antigen antibody [Pab 430]
See all SV40 T-antigen products (6) ...
Description
Mouse monoclonal [Pab 430] to SV40 T-antigen
Tested applications
WB, RIAmore details
Cross reactivity
Reacts with
Simian Virus 40 (SV40)
Immunogen
SV40 transformed mouse cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
Pab 430
Myeloma
P3-NS1/1-Ag4-1
Isotype
IgG3
Research areas
Cancer >> Oncoproteins/suppressors >> Viral proteins >> SV40 antigen
Microbiology >> Organism >> Virus >> DNA Virus >> double stranded DNA Virus >> Other dsDNA viruses
Applications
Show applications key
Our Abpromise guarantee covers the use of ab20249 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 82 kDa.
RIA: Use at an assay dependent dilution.
Target
Relevance
SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
Cellular localization
Nuclear
Alternative names
- Large T antigen antibody
- LT AG antibody
- LT antibody
see all
Database links
- Entrez Gene: 1489531 Simian Virus 40 (SV40)
- SwissProt: P03070 Simian Virus 40 (SV40)
References for Anti-SV40 T-antigen antibody [Pab 430] (ab20249)
ab20249 has not yet been referenced specifically in any publications.
Publishing research using ab20249? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"