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Anti-Securin antibody [DCS-280] (ab3305)

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Publishing research using ab3305? Please let us know so that we can cite the reference in this datasheet

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ab3305 has been referenced in 28 publications.

  1. Tseng HH et al. Securin Enhances the Anti-Cancer Effects of 6-Methoxy-3-(3',4',5'-Trimethoxy-Benzoyl)-1H-Indole (BPR0L075) in Human Colorectal Cancer Cells. PLoS One 7:e36006 (2012). WB; Human. PubMed: 22563433
  2. Holt JE et al. The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes. Development 138:905-13 (2011). PubMed: 21270054
  3. Chang HY et al. Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720. J Biol Chem 286:14705-12 (2011). PubMed: 21383018
  4. Kannan RP et al. Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis. J Virol 85:7989-8001 (2011). WB; Human. PubMed: 21680513
  5. Olsen JV et al. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3:ra3 (2010). PubMed: 20068231
  6. Dulla K et al. Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9:1167-81 (2010). WB; Human. PubMed: 20097925
  7. Keppner S et al. Biological impact of freezing Plk1 in its inactive conformation in cancer cells. Cell Cycle 9:761-73 (2010). WB; Human. PubMed: 20139717
  8. van Zon W et al. The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit. J Cell Biol 190:587-602 (2010). PubMed: 20733055
  9. Huang YT et al. TrkB antibody elicits cytotoxicity and suppresses migration/invasion of transitional cell carcinoma cells. Int J Oncol 37:943-9 (2010). PubMed: 20811716
  10. van Ree JH et al. Overexpression of the E2 ubiquitin-conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation. J Cell Biol 188:83-100 (2010). WB; Mouse. PubMed: 20065091
  11. Gurden MD et al. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. J Cell Sci 123:321-30 (2010). WB; Human. PubMed: 20053638
  12. Zhou C et al. E2F1 induces pituitary tumor transforming gene (PTTG1) expression in human pituitary tumors. Mol Endocrinol 23:2000-12 (2009). PubMed: 19837943
  13. Gaitanos TN et al. Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J 28:1442-52 (2009). WB; Human. PubMed: 19360002
  14. Talvinen K et al. Securin promotes the identification of favourable outcome in invasive breast cancer. Br J Cancer 101:1005-10 (2009). PubMed: 19690544
  15. Marangos P & Carroll J Securin regulates entry into M-phase by modulating the stability of cyclin B. Nat Cell Biol 10:445-51 (2008). WB, ICC/IF; Mouse. PubMed: 18364698
  16. Talvinen K et al. Proliferation marker securin identifies favourable outcome in invasive ductal breast cancer. Br J Cancer 99:335-40 (2008). IHC-P; Human. PubMed: 18594525
  17. Qiao D et al. Glypican-1 regulates anaphase promoting complex/cyclosome substrates and cell cycle progression in endothelial cells. Mol Biol Cell 19:2789-801 (2008). WB; Mouse. PubMed: 18417614
  18. Lee SH et al. Tpr directly binds to Mad1 and Mad2 and is important for the Mad1-Mad2-mediated mitotic spindle checkpoint. Genes Dev 22:2926-31 (2008). IP; Human. PubMed: 18981471
  19. Niault T et al. Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I. PLoS ONE 2:e1165 (2007). WB; Mouse. PubMed: 18043727
  20. Ngo TT et al. The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureas. J Natl Cancer Inst 99:639-52 (2007). PubMed: 17440165
  21. Liu CL et al. L2dtl is essential for cell survival and nuclear division in early mouse embryonic development. J Biol Chem 282:1109-18 (2007). PubMed: 17107960
  22. Reis A et al. Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes. Nat Cell Biol 9:1192-8 (2007). WB; Mouse. PubMed: 17891138
  23. Keck JM et al. Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). J Cell Biol 178:371-85 (2007). WB; Human. PubMed: 17664332
  24. Chao JI et al. Depletion of Securin Increases Arsenite-Induced Chromosome Instability and Apoptosis via a p53-Independent Pathway. Toxicol Sci 90:73-86 (2006). PubMed: 16338954
  25. Chao JI & Liu HF The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. Mol Pharmacol 69:154-64 (2006). PubMed: 16219911
  26. Huo LJ et al. Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition. Front Biosci 11:2193-202 (2006). PubMed: 16720305
  27. Holland AJ & Taylor SS Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction. J Cell Sci 119:3325-36 (2006). ICC/IF. PubMed: 16868023
  28. Chen Z et al. A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth. Mol Cancer Ther 4:562-8 (2005). PubMed: 15827329

Publishing research using ab3305? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"