Serotonin hydrochloride (5-HT/5-Hydroxytryptamine), 5-HT receptor agonist (ab120528)
Key features and details
- Endogenous neurotransmitter, 5-HT receptor agonist
- CAS Number: 153-98-0
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Serotonin hydrochloride (5-HT/5-Hydroxytryptamine), 5-HT receptor agonist -
Description
Endogenous neurotransmitter, 5-HT receptor agonist -
Alternative names
- 5-HT
- 5-Hydroxytryptamine
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Biological description
Endogenous 5-HT receptor agonist. Neurotransmitter involved in diverse physiological functions such as mood, appetite, sleep, sex and temperature in addition to modulating cardiovascular function and the gastrointestinal system. Also a 5-HT transporter substrate.
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CAS Number
153-98-0 -
Chemical structure
Properties
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Chemical name
3-(2-Aminoethyl)-5-hydroxyindole hydrochloride -
Molecular weight
212.68 -
Molecular formula
C10H12N2O.HCl -
PubChem identifier
160436 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC2=C(C=C1O)C(=CN2)CCN.Cl -
Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab120528 has been referenced in 2 publications.
- Lim I et al. Altered ureteral contractility with ageing: Role of the rho-kinase pathway. Mech Ageing Dev 171:31-36 (2018). PubMed: 29530787
- Foster JD et al. Nitric oxide-mediated modulation of the murine locomotor network. J Neurophysiol 111:659-74 (2014). PubMed: 24259545