Anti-Smac / Diablo antibody [8H5AB2] (ab110291)
- Product nameAnti-Smac / Diablo antibody [8H5AB2]See all Smac / Diablo primary antibodies ...
- DescriptionMouse monoclonal [8H5AB2] to Smac / Diablo
- Tested applicationsWB more details
- Species reactivityReacts with: Human
Recombinant Smac, TIMM22 proteins
- Positive controlHuman liver mitochondria and HepG2 cells
- Storage instructionsStore at +4°C. Do not freeze.
- Storage bufferPreservative: 0.02% Sodium azide
- Concentration information loading...
- PurityAmmonium Sulphate Precipitation
- Purification notesPurity near homogeneity as judge by SDS-PAGE. The antibody was produced in-vitro using hybridomas grown in serum-free medium and then purified by biochemical fractionation.
- Clonality Monoclonal
- Clone number8H5AB2
- Light chain typekappa
Our Abpromise guarantee covers the use of ab110291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.|
- FunctionPromotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
- Tissue specificityUbiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
- DomainThe mature N-terminus mediates interaction with XIAP.
- Cellular localizationMitochondrion. Released into the cytosol when cells undergo apoptosis.
- 0610041G12Rik antibodyDBLOH_HUMAN antibodyDBOH antibody
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Anti-Smac / Diablo antibody [8H5AB2] images
All lanes : Anti-Smac / Diablo antibody [8H5AB2] (ab110291) at 1 µg/ml
Lane 1 : Human liver mitichondria
Lane 2 : HepG2 cells
Predicted band size : 27 kDa
References for Anti-Smac / Diablo antibody [8H5AB2] (ab110291)
ab110291 has not yet been referenced specifically in any publications.