Anti-Somatostatin Receptor 1 antibody (ab100881)

Overview

  • Product name
    Anti-Somatostatin Receptor 1 antibody
    See all Somatostatin Receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Somatostatin Receptor 1
  • Tested applications
    Suitable for: WB, IHC-P, ICC, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Horse, Cow, Dog, Human, Pig
  • Immunogen

    Synthetic peptide:

    ESGGVFRNGTCASRISTL

    , corresponding to C terminal amino acids 374-391 of Mouse and Rat Somatostatin Receptor 1

Properties

Applications

Our Abpromise guarantee covers the use of ab100881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000. Predicted molecular weight: 43 kDa.
IHC-P 1/2000.
ICC 1/5000.
ICC/IF Use at an assay dependent concentration.

Target

  • Function
    Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
  • Tissue specificity
    Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G-protein coupled receptor antibody
    • Somatostatin R1 antibody
    • Somatostatin receptor 1 antibody
    • Somatostatin receptor isoform 1 antibody
    • Somatostatin receptor type 1 antibody
    • SRIF 2 antibody
    • SRIF-2 antibody
    • SRIF2 antibody
    • SS-1-R antibody
    • SS1 R antibody
    • SS1-R antibody
    • SS1R antibody
    • SSR1_HUMAN antibody
    • SSTR 1 antibody
    • Sstr1 antibody
    see all

Images

  • ab100881 at 1/5000 showing dual labeling of anti-sst1 (green) and somatostatin (red). Anti-Sst1 shows sst1 in neuronal terminals co-localized with somatostatin
  • ab100881 showing anti-Sst1 depicts sst1 as a presynaptic receptor in the superficial layers of the spinal cord dorsal horn

References

ab100881 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step
nomal goat serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Antigen retrieval step
None
Sample
Mouse Tissue sections (Brain)
Specification
Brain
Permeabilization
Yes - 0,3% Triton X100
Fixative
Paraformaldehyde
Username

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Verified customer

Submitted Nov 13 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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