Somatostatin Receptor 1 antibody (ab2366)

Product Name 

Somatostatin Receptor 1 antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to Somatostatin Receptor 1

Immunogen 

Synthetic peptide (Rat)A synthetic peptide derived from the C-terminus of rat somatostatin receptor 1

Reacts with 
(species key)

Hu, Ms, Rat

Specificity 

This antibody reacts with a 60 kD protein, known as Somatostatin Receptor 1.

Tested applications 
(see key)

IHC-Fr, IHC-P

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IHC-P: 1/50 - 1/75 in an ABC method. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
IHC-Fr: 1/50 - 1/75 in an ABC method.
We suggest an incubation period of 30 minutes at room temperature.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Pancreas

Cellular localization 

Cell Membrane

Research areas 

Neuroscience >> Neurology process >> Neuroendocrinology >> GH Regulation
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> More GPCR
Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones

Relevance 

Somatostatin Receptor (SSTR) 1 is one of the five receptor subtypes termed SSTR 1 to 5. They are G-protein-coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system.

The Somatostatin family of receptors have five members, sst1-sst5, as well as two isoforms of Somatostatin receptor 2, sst2A and sst2B.
They are coupled to G protein and are involved in regulation of numerous processes including secretion of insulin, glucagons and growth hormone and excitation of neurons in central and peripheral nervous system.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.05% Sodium Azide
Constituents: 1% BSA

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Storage instructions 

Store at +4°C.

See below for Somatostatin Receptor 1 antibody images, references, products related to ab2366 and other tools.

Somatostatin Receptor 1 antibody images:

Customer reviews (feedback) regarding Somatostatin Receptor 1 antibody

Customer FAQs regarding Somatostatin Receptor 1 antibody

Protocols for Somatostatin Receptor 1 antibody

Price and availability of products related to Somatostatin Receptor 1 antibody

Somatostatin Receptor 1 antibody - related products: