|
|
|
|
|
Product Name
|
Somatostatin Receptor 1 antibody
|
| |
See all Somatostatin Receptor 1 antibodies (3)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to Somatostatin Receptor 1
|
|
Immunogen
|
Synthetic peptide from the amino terminus, corresponding to the 1st extracellular domain of the rat sequence conjugated to KLH.
|
|
Reacts with
(species key)
|
Hu, Rat
|
|
Epitope
|
Amino terminal 1st extracellular domain and 2nd and 3rd extracellular
loops.
|
|
Tested applications
(see key)
|
ELISA, WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
ELISA: 1/500.
WB: 1/500 - 1/1000. Detects a band of approximately 53 kDa in Mia PaCa-2 cell membrane extracts (predicted molecular weight: 47 kDa). This is consistent with the
glycosylated form of the receptor (see Helboe et al, PMID 9387866) though lower than 60 kDa reported elsewhere (see Gu et al PMID 8847999 and Hadcock et al PMID 8145728).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
PaCa 2 human pancreatic cells transfected with somatostatin receptor 1.
|
|
Cellular localization
|
Cell Membrane
|
|
Research areas
|
Neuroscience >> Neurology process >> Neuroendocrinology >> GH Regulation
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> More GPCR
Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones
|
|
Relevance
|
Somatostatin Receptor (SSTR) 1 is one of the five receptor subtypes termed SSTR 1 to 5. They are G-protein-coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system.
|
|
|
Somatostatin Receptor 1 antibody (ab5827) |
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Whole antiserum
|
|
Storage buffer
|
Preservative: None
Constituents: Whole Serum
|
|
Form
|
Liquid
|
|
Concentration
|
Concentration not determined - why is this?
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Somatostatin Receptor 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to Somatostatin Receptor 1
|
| |
Somatostatin Receptor 1 antibody - more information
|
Customer reviews (feedback) regarding Somatostatin Receptor 1 antibody |
Customer FAQs regarding Somatostatin Receptor 1 antibody |
Protocols for Somatostatin Receptor 1 antibody |
Price and availability of products related to Somatostatin Receptor 1 antibody |
| |
Somatostatin Receptor 1 antibody - related products:
|
|
|
| |
Somatostatin Receptor 1 antibody - other tools:
|
Contact Abcam with a Technical Enquiry about Somatostatin Receptor 1 antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
