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Anti-Somatostatin Receptor 2 antibody (ab9550)

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Overview

Product name

Anti-Somatostatin Receptor 2 antibody

Description

Rabbit polyclonal to Somatostatin Receptor 2

Specificity

This antibody is specific for Somatostatin R2

Tested applications

WB, ICC/IF, IHC-Pmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide: C-ERSDSKQDKSRLNETTETQRT conjugated to KLH, corresponding to C terminal amino acids 339-359 of Rat Somatostatin Receptor 2.

C-ERSDSKQD KSRLNETTET QRT

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

serum with 0.05% sodium azide

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

unknown

Light chain type

unknown

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Neuroscience >> Neurology process >> Neuroendocrinology >> GH Regulation
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> More GPCR
Neuroscience >> Neurotransmitter >> Neuropeptides >> Hormones

Applications

Show applications key

Our Abpromise guarantee covers the use of ab9550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: 1/100 - 1/1000.( (75...Read more →

    WB: 1/100 - 1/1000.( (75-85 kDa band expected).Multiple smaller MW bands may also be seen.)

  • ICC/IF

     ICC/IF: 1/100 - 1/250.

    ICC/IF: 1/100 - 1/250.

  • ShowHide

    IHC-P

     IHC-P: Use at an assay d...Read more →

    IHC-P: Use at an assay dependent dilution.

Target

Function

Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels.

Tissue specificity

Cerebrum and kidney. In lesser amounts in jejunum, colon and liver.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Cellular localization

Cell membrane.

Target information above from: UniProt accessionP30874 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Somatostatin receptor type 2 antibody
  • SRIF-1 antibody
  • SRIF1 antibody
  • SS-2-R antibody
  • SS2-R antibody
  • SS2R antibody
  • SSR2_HUMAN antibody
  • SST2 antibody
  • SSTR2 antibody
see all

Database links

see all

References for Anti-Somatostatin Receptor 2 antibody (ab9550)

This product has been referenced in:

  • Fasciani Aet al. Overexpression and functional relevance of somatostatin receptor-1, -2, and -5 in endometrium and endometriotic lesions. J Clin Endocrinol Metab 95:5315-9 (2010). IHC-P; Human.Read more (PubMed: 20739383) »

See 1 publication for this product

Publishing research using ab9550? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"