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Product name
Anti-Stargazin antibody
See all Stargazin products (3) ...
Description
Rabbit polyclonal to Stargazin
Tested applications
WB, IHC-P, IHC-Frmore details
Cross reactivity
Reacts with
Mouse, Rat
Immunogen
A synthetic peptide from the C terminal region of Mouse Stargazin conjugated to an immunogenic carrier protein. The peptide is homologous in rat.
Positive control
Rat spinal cord
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Signaling Pathway >> Calcium Signaling >> Calcium Channels
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
(enlarge)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
(enlarge)
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab104590 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/300 - 1/2000. Predicted molecular weight: 36 kDa.This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
IHC-P: 1/300 - 1/2000. Antigen retrieval recommended.
IHC-Fr
IHC-Fr: 1/300 - 1/2000.IHC-Fr: 1/300 - 1/2000.
Target
Function
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Tissue specificity
Brain.
Sequence similarities
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Post-translational
modifications
Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.
Cellular localization
Membrane.
Target information above from: UniProt accessionQ9Y698
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- AW060990 antibody
- B230105C07Rik antibody
- B930041E13Rik antibody
see all
Database links
- Entrez Gene: 12300 Mouse
- Entrez Gene: 84347 Rat
- SwissProt: O88602 Mouse
- SwissProt: Q71RJ2 Rat
- Unigene: 277338 Mouse
- Unigene: 400802 Mouse
- Unigene: 72939 Rat
Anti-Stargazin antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
ab104590 at 1/300 dilution (incubated overnight at 4C) detecting Stargazin in rat spinal cord by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
ab104590 at 1/300 dilution (incubated overnight at 4C) detecting Stargazin in rat spinal cord by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
ab104590 at 1/300 dilution (incubated overnight at 4C) detecting Stargazin in rat spinal cord by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
ab104590 at 1/300 dilution (incubated overnight at 4C) detecting Stargazin in rat spinal cord by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Stargazin antibody (ab104590)
ab104590 at 1/300 dilution (incubated overnight at 4C) detecting Stargazin in rat spinal cord by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
References for Anti-Stargazin antibody (ab104590)
ab104590 has not yet been referenced specifically in any publications.
Publishing research using ab104590? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"