Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Overview
Product name
Anti-Stathmin 1 antibody
See all Stathmin 1 products (19) ...
Description
Rabbit polyclonal to Stathmin 1
Specificity
The immunogen sequence is not found in other members of the Stathmin family such as SCG10, RB3, and XB3.
Tested applications
IHC-P, WBmore details
Cross reactivity
Reacts with
Rat, Human
Predicted to work with
Mouse
Immunogen
Synthetic peptide, corresponding to C terminal amino acids 132-149 of Human Stathmin 1
Positive control
Whole cell extract of the human acute lymphoma Jurkat cell line. Cytosolic fraction of rat brain. Human tonsil.
General notes
Storage in frost-free freezers is not recommended.
If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Working dilutions should be discarded if not used within 12 hours.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4
Concentration
Concentration information loading...
Purity
IgG fraction
Purification notes
Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> Tubulin
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
Applications
Show applications key
Our Abpromise guarantee covers the use of ab11269 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P
WB
Application notes
IHC-P: 1/500. This concentration was determined for sections of human tonsil.
WB: 1/2000. Staining of Stathmin in WB is specifically inhibited with Stathmin immunizing peptide. Detects a band of approximately 19 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
This protein is a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Alternatively spliced transcript variants encoding the same protein have been identified.
Cellular localization
Cytoplasmic
Alternative names
- C1orf215 antibody
- Lag antibody
- LAP 18 antibody
see all
Database links
- Entrez Gene: 3925 Human
- Entrez Gene: 16765 Mouse
- Entrez Gene: 29332 Rat
- Omim: 151442 Human
- SwissProt: P16949 Human
- SwissProt: P54227 Mouse
- SwissProt: P13668 Rat
- Unigene: 209983 Human
see all
References for Anti-Stathmin 1 antibody (ab11269)
This product has been referenced in:
- Spicakova Tet al. Expression and silencing of the microtubule-associated protein Tau in breast cancer cells. Mol Cancer Ther 9:2970-81 (2010). WB; Human.Read more (PubMed: 21062914) »
- Passer BJet al. Oncolytic herpes simplex virus vectors and taxanes synergize to promote killing of prostate cancer cells. Cancer Gene Ther 16:551-60 (2009). WB; Human.Read more (PubMed: 19197321) »
See all 3 publications for this product
Publishing research using ab11269? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"