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Staurosporine

Product code: ab120056 (formerly Asc-056)

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Overview

Product name

Staurosporine

Biological description

Potent, cell permeable, broad spectrum inhibitor of protein kinases. Kinases inhibited include: protein kinase C (IC50 = 3 nM), cAMP-dependent protein kinase (IC50 = 8 nM), and p60v-src (IC50 = 6 nM).

Purity

> 98%

General notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Properties

Chemical name

[9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3,2,1-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one

Molecular Weight

466.54

Chemical structure

Chemical Structure

Molecular formula

C28H26N4O3

CAS Number

62996-74-1

Solubility

Soluble in DMSO to 50 mM

Storage instructions

Store at +4°C (desiccating conditions). Do not freeze.

References for Staurosporine (ab120056)

This product has been referenced in:

  • Gadbois DM  et al. Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases. Biochem Biophys Res Commun 184:80-5 (1992).Read more (PubMed: 1567459) »

See 1 publication for this product

Publishing research using ab120056? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"