Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Microbiology >> Organism >> Bacteria >> Gram positive bacteria >> Streptococcus
Overview
Product name
Streptolysin O (Hemolytic streptococcus) protein (Active)
Protein description
The product was highly purified from E.coli over-expressing Streptolysin O of Group C hemolytic streptococci.
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Purification notes
Purity >98% SDS-PAGE.
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 50% Glycerol, PBS, 1mM DTT
Concentration
Concentration information loading...
Research areas
Microbiology >> Toxin >> Bacterial Toxin >> Streptococcus Toxin
Microbiology >> Organism >> Bacteria >> Gram positive bacteria >> Streptococcus
-
SDS-PAGE - Streptolysin protein (ab63978)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab63978 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
FuncS: Use at an assay dependent dilution. (The specific activity is as high as 700,000 to ~1,900,000 hemolytic units (HU) /mg. Definition of 1HU is the activation of 50% hemolysis on 3% sheep red blood cells. Restoration of activity can be done by 20 mM cysteine or 10 mM DTT. )
Protein info
Relevance
Streptolysin O (SLO) is a membrane-damaging extracellular toxin produced by hemolytic streptococci. The membrane-damaging activity is measured by hemolysis of red-blood cell. SLO is oxygen-sensitive and is easily inactivated in its presence but can be reactivated by thiol compounds , so it is also called thiol-activated cytolysin (2). SLO is produced not only by Group A hemolytic streptococci but also by Group C and Group G strains. The amino acid sequences are highly conserved among them and their homology is over 98%.
Streptolysin O (Hemolytic streptococcus) protein (Active) images:
References for Streptolysin O (Hemolytic streptococcus) protein (Active) (ab63978)
ab63978 has not yet been referenced specifically in any publications.
Publishing research using ab63978? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"