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Products:Cell Biology >> Other Antibodies >> Oxidative Stress
Overview
Product name
Anti-Superoxide Dismutase 3 antibody
See all Superoxide Dismutase 3 products (6) ...
Description
Rabbit polyclonal to Superoxide Dismutase 3
Tested applications
Cross reactivity
Reacts with
Mouse, Rat, Human
Predicted to work with
Rabbit
Immunogen
Synthetic peptide derived from Superoxide Dismutase 3
Positive control
Rat and mouse Lung Tissue Extract; Human Superoxide Dismutase 3 Protein.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 50% Glycerol, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Cellular metabolic process
Cancer >> Cancer Metabolism >> Response to hypoxia
Cell Biology >> Other Antibodies >> Oxidative Stress
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Western blot - Superoxide Dismutase 3 antibody (ab83108)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab83108 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000Detects a band of approximately 35 kDa (predicted molecular weight: 26 kDa).
Target
Function
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Tissue specificity
Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Sequence similarities
Belongs to the Cu-Zn superoxide dismutase family.
Cellular localization
Secreted > extracellular space. 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium.
Target information above from: UniProt accessionP08294
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- EC SOD antibody
- EC-SOD antibody
- Extracellular superoxide dismutase [Cu Zn] antibody
see all
Database links
- Entrez Gene: 6649 Human
- Entrez Gene: 20657 Mouse
- Entrez Gene: 25352 Rat
- Omim: 185490 Human
- SwissProt: P08294 Human
- SwissProt: Q6FHA2 Human
- SwissProt: O09164 Mouse
- SwissProt: O88592 Mouse
see all
Anti-Superoxide Dismutase 3 antibody images:
Western blot - Superoxide Dismutase 3 antibody (ab83108)
All lanes : Anti-Superoxide Dismutase 3 antibody (ab83108) at 1/1000 dilution
Lane 1 : Rat lung tissue extract
Lane 2 : Mouse lung tissue extract
Lane 3 : Human Superoxide Dismutase 3 protein
developed using the ECL technique
Predicted band size : 26 kDa
Observed band size : 35 kDa (why is the actual band size different from the predicted?)
Additional bands at : 40 kDa (possible glycosylated form),60 kDa (possible dimer).
References for Anti-Superoxide Dismutase 3 antibody (ab83108)
ab83108 has not yet been referenced specifically in any publications.
Publishing research using ab83108? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"