You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Survivin antibody (ab469)

CodeSizePriceAbpointsAvailability
    
 
  • -

  •   
  •   
  •   
  •  

  •  
  •  
  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Publishing research using ab469? Please let us know so that we can cite the reference in this datasheet

Show applications key

ab469 has been referenced in 35 publications.

  1. Kaminskyy VO et al. Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL. Carcinogenesis 32:1450-8 (2011). PubMed: 21771726
  2. Dallaglio K et al. Endogenous survivin modulates survival and proliferation in UVB-treated human keratinocytes. Exp Dermatol 18:464-71 (2009). WB; Human. PubMed: 19320741
  3. Ferri F et al. Non-coding murine centromeric transcripts associate with and potentiate Aurora B kinase. Nucleic Acids Res 37:5071-80 (2009). WB, RIP; Mouse. PubMed: 19542185
  4. Bourguignon LY et al. Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microrna-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells. J Biol Chem 284:26533-46 (2009). WB; Human. PubMed: 19633292
  5. Platani M et al. The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell 20:5260-75 (2009). ICC/IF; Human. PubMed: 19864462
  6. Maerki S et al. The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J Cell Biol 187:791-800 (2009). ICC/IF; Human. PubMed: 19995937
  7. Lampiasi N et al. Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism. Mol Pharmacol 76:290-300 (2009). PubMed: 19461054
  8. Kwong J et al. An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells. Mol Cancer Ther 8:1893-905 (2009). PubMed: 19567818
  9. Benedetti V et al. Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds. Mol Cancer Ther 7:679-87 (2008). WB; Human. PubMed: 18347153
  10. Pellizzaro C et al. Inhibition of human pancreatic cell line MIA PaCa2 proliferation by HA-But, a hyaluronic butyric ester: a preliminary report. Pancreas 36:e15-23 (2008). WB; Human. PubMed: 18437074
  11. Donovan MH et al. Dynamic expression of TrkB receptor protein on proliferating and maturing cells in the adult mouse dentate gyrus. Hippocampus 18:435-9 (2008). PubMed: 18240316
  12. Dance-Barnes ST et al. Effects of mutant human Ki-ras(G12C) gene dosage on murine lung tumorigenesis and signaling to its downstream effectors. Toxicol Appl Pharmacol 231:77-84 (2008). IHC-P; Mouse. PubMed: 18565564
  13. Végran F et al. Association of p53 gene alterations with the expression of antiapoptotic survivin splice variants in breast cancer. Oncogene 26:290-7 (2007). PubMed: 16847456
  14. Hinnis AR et al. Survivin is an independent predictor of short-term survival in poor prognostic breast cancer patients. Br J Cancer 96:639-45 (2007). PubMed: 17285125
  15. Barnes N et al. Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence. Br J Cancer 94:253-8 (2006). IHC-P; Human. PubMed: 16421596
  16. Klein UR et al. Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell 17:2547-58 (2006). PubMed: 16571674
  17. Colnaghi R et al. Separating the anti-apoptotic and mitotic roles of survivin. J Biol Chem 281:33450-6 (2006). PubMed: 16950794
  18. Santini D et al. Cyclooxygenase-2 overexpression is associated with a poor outcome in resected ampullary cancer patients. Clin Cancer Res 11:3784-9 (2005). PubMed: 15897577
  19. Rödel F et al. Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer. Cancer Res 65:4881-7 (2005). IHC-P; Human. PubMed: 15930309
  20. Zanchi C et al. Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839. Cancer Res 65:2364-72 (2005). WB; Human. PubMed: 15781651
  21. Branca M et al. Survivin as a marker of cervical intraepithelial neoplasia and high-risk human papillomavirus and a predictor of virus clearance and prognosis in cervical cancer. Am J Clin Pathol 124:113-21 (2005). IHC-P. PubMed: 15923164
  22. Sommer KW et al. Inhibitor of apoptosis protein (IAP) survivin is upregulated by oncogenic c-H-Ras. Oncogene 22:4266-80 (2003). PubMed: 12833149
  23. Kennedy SM et al. Prognostic importance of survivin in breast cancer. Br J Cancer 88:1077-83 (2003). PubMed: 12671708
  24. Grabowski P et al. Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma. Br J Cancer 88:115-9 (2003). PubMed: 12556969
  25. Miranda MB et al. Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells. Leukemia 17:390-400 (2003). PubMed: 12592339
  26. Mahotka C et al. Differential subcellular localization of functionally divergent survivin splice variants. Cell Death Differ 9:1334-42 (2002). PubMed: 12478470
  27. Chakravarti A et al. Quantitatively determined survivin expression levels are of prognostic value in human gliomas. J Clin Oncol 20:1063-8 (2002). PubMed: 11844831
  28. Fortugno P et al. Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci 115:575-85 (2002). PubMed: 11861764
  29. Giodini A et al. Regulation of microtubule stability and mitotic progression by survivin. Cancer Res 62:2462-7 (2002). PubMed: 11980633
  30. Yu J et al. Increased expression of survivin in gastric cancer patients and in first degree relatives. Br J Cancer 87:91-7 (2002). PubMed: 12085263
  31. O'Connor DS et al. A p34(cdc2) survival checkpoint in cancer. Cancer Cell 2:43-54 (2002). PubMed: 12150824
  32. Blanc-Brude OP et al. Inhibitor of apoptosis protein survivin regulates vascular injury. Nat Med 8:987-94 (2002). PubMed: 12172543
  33. Qanungo S et al. 2-Methoxyestradiol induces mitochondria dependent apoptotic signaling in pancreatic cancer cells. Oncogene 21:4149-57 (2002). PubMed: 12037671
  34. Zhu L et al. Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. FEBS Lett 508:369-74 (2001). PubMed: 11728454
  35. Wheatley SP et al. INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis. Curr Biol 11:886-90 (2001). PubMed: 11516652

Publishing research using ab469? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"