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- Secondary antibodies
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Product name
Anti-Synaptobrevin antibody
See all Synaptobrevin products (6) ...
Description
Sheep polyclonal to Synaptobrevin
Specificity
ab28362 recognises VAMP (Synaptobrevin)-1/2.
Tested applications
WB, IPmore details
Cross reactivity
Reacts with
Rat
Immunogen
The details of the immunogen for this antibody are not available.
Positive control
Rat synaptic vesicles
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.08% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Purification notes
Purified by ammonium sulfate precipitation.
Clonality
Polyclonal
Isotype
IgG
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Integration of energy
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Neuroscience >> Neurotransmission >> Secretory Vesicles >> SNAPs & SNAREs
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28362 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 10 ��g/ml. Predicted molecular weight: 13 kDa.
IP: Use a concentration of 5 - 15 µg/ml.
Target
Relevance
Synaptobrevins are highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Synaptobrevins, Syntaxins, and the 25 kDa synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane.
Cellular localization
Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane. Single-pass type IV membrane protein. Cell junction > synapse > synaptosome. Isoform 3 is found in mitochondria, mitochondrial outer membrane.
Alternative names
- SYB antibody
- SYB1 antibody
- Synaptobrevin 1 antibody
see all
Database links
References for Anti-Synaptobrevin antibody (ab28362)
ab28362 has not yet been referenced specifically in any publications.
Publishing research using ab28362? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"