Anti-Synaptotagmin VII antibody (ab106618)
Key features and details
- Rabbit polyclonal to Synaptotagmin VII
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-Synaptotagmin VII antibody
See all Synaptotagmin VII primary antibodies -
Description
Rabbit polyclonal to Synaptotagmin VII -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat
Predicted to work with: Rabbit, Human, Chimpanzee, Macaque monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide corresponding to Human Synaptotagmin VII aa 50-150 conjugated to keyhole limpet haemocyanin.
(Peptide available asab154624) -
Positive control
- WB: Mouse and Rat Brain tissue lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106618 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Abcam recommends using milk as the blocking agent - 3%.
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Notes |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). Abcam recommends using milk as the blocking agent - 3%. |
Target
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Function
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. -
Tissue specificity
Expressed in a variety of adult and fetal tissues. -
Sequence similarities
Belongs to the synaptotagmin family.
Contains 2 C2 domains. -
Domain
The second C2 domain/C2B is responsible for SYNCRIP binding. -
Cellular localization
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. - Information by UniProt
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Database links
- Entrez Gene: 9066 Human
- Entrez Gene: 54525 Mouse
- Entrez Gene: 59267 Rat
- Omim: 604146 Human
- SwissProt: O43581 Human
- SwissProt: Q9R0N7 Mouse
- Unigene: 502730 Human
- Unigene: 684589 Human
see all -
Alternative names
- IPCA 7 antibody
- IPCA-7 antibody
- IPCA7 antibody
see all
Images
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All lanes : Anti-Synaptotagmin VII antibody (ab106618) at 1 µg/ml
Lane 1 : Mouse Brain Tissue lysate
Lane 2 : Rat Brain Tissue lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/50000 dilution
Predicted band size: 45 kDa
Observed band size: 45 kDa
Exposure time: 8 minutesBlocking buffer: 3% Milk
Gel type: MOPS
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab106618 has been referenced in 1 publication.
- Sidoryk-Wegrzynowicz M et al. Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions. Acta Neuropathol Commun 5:89 (2017). WB . PubMed: 29187256