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Product Name
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Synphilin 1 antibody
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See all Synphilin 1 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Synphilin 1
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Immunogen
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Synthetic peptide: SLELNGEKDKDKGRTLQRTC conjugated to KLH by a Glutaraldehyde linker, corresponding to amino acids 829-847 of Human Synphilin 1. BLAST 'SLELNGEKDKDKGRTLQRTC' with or 
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Reacts with
(species key)
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Hu, Rat
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Specificity
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Immunohistochemical analysis of human brain indicates a high level of specificity for this antiserum.
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Tested applications
(see key)
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IHC-Fr, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions Immunohistochemistry: 1/2,000 Western Blot: Not tested. Immunoblot: Not tested. 1 site ELISA: Not tested. Biological Inhibition: Not tested.
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Cellular localization
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Cytoplasmic
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Research areas
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Neuroscience >> Neurology process >> Neurodegenerative disease >> Parkinson's disease >> Other Neuroscience >> Neurology process >> Neurodegenerative disease >> Parkinson's disease >> Synuclein
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Relevance
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This protein contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of Synphilin 1 have been linked to Parkinson disease.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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n/a
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C (add glycerol to a final volume of 50% for extra stability). Avoid repeated freeze / thaw cycles.
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Notes
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This antibody will stain Lewy bodies in Dorsal raphe nucleus of Parkinson’s diseased human brain.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Synphilin 1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Synphilin 1
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Synphilin 1 antibody - more information
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Customer reviews (feedback) regarding Synphilin 1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"