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Overview

  • Product nameTAB1 protein (Tagged-His Tag)See all TAB1 proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 4-504 (501 amino acids) of Human TAB1 with N terminal His tag; Predicted MWt 55 kDa (UniProt Q15750).
  • Expression hostE. coli

    • Properties

  • Purification notesPurity level >85%
    This protein was expressed as an N-terminal His-tag fusion protein using Escherichia coli, and purified using Immobilized Metal Ion Affinity Chromatography. In some cases, smaller protein fragments may be present in addition to the intended expression product as a result of premature termination during translation in E. coli and subsequent co-purification via the His-tag. In some cases purified proteins run at a molecular weight different to the theoretically calculated molecular weight. This may be as a result of unequally distributed charges in the amino acid sequence. Alternatively, dimerisation of the expression product can occur under oxygen limitation during expression/cultivation.
  • FormLyophilised:Reconstitute with 108 µl aqua dest.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
  • Concentration information loading...
  • Additional notesProtein Identity confirmed by Mass Spectrometry (MS/MS) (acquired on initial reference batch)
  • Sequence notesQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKG TESHPPEDS WLKFRSENNCFLYGVFNGYDGNRVTNFVA QRLSAELLLGQLNAEHAEAD VRRVLLQAFDVVERSFLE SIDDALAEKASLQSQLPEGVPQHQLPPQYQK ILERLKT LEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG LQ VTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIIC GQESTRRIGDYKV KYGYTDIDLLSAAKSKPIIAEPEIH GAQPLDGVTGFLVLMSEGLYKALE AAHGPGQANQEIAA MIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGG ERA RFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYP VSVPYS SAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL DEATPTLTNQSPTLTLQ STNTHTQSSSSSSDGGLFRSR PAHSLPPGEDGRVEPYVDFAEFYRLWSV DHGEQSVVTA P
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab91998 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    MS
    SDS-PAGE
  • Application notesMS: Use at an assay dependent dilution.
    SDS-PAGE: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        2310012M03Rik3'-Tab1MAP3K7IP 1
        MAP3K7IP1MGC57664Mitogen activated protein kinase kinase kinase 7 interacting protein 1Mitogen-activated protein kinase kinase kinase 7-interacting protein 1TAB 1TAB1TAB1_HUMANTAK1 binding protein 1TAK1-binding protein 1TGF beta activated kinase 1 binding protein 1TGF-beta activated kinase 1/MAP3K7 binding protein 1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1TGF-beta-activated kinase 1-binding protein 1Transforming growth factor beta activated kinase binding protein 1
      see all
  • FunctionMay be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 PP2C-like domain.
  • Post-translational
    modifications    Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.

    • Target information above from: UniProt accession Q15750 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    TAB1 protein (Tagged-His Tag) images

    • SDS-PAGE - TAB1 protein (Tagged-His Tag) (ab91998)
      SDS-PAGE - TAB1 protein (Tagged-His Tag) (ab91998)
      The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.

    References for TAB1 protein (Tagged-His Tag) (ab91998)

    ab91998 has not yet been referenced specifically in any publications.

    Publishing research using ab91998 ? Please let us know so that we can cite the reference in this datasheet

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