Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Related products
- Secondary antibodies
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Anti-TAB1 antibody
See all TAB1 products (8) ...
Description
Rabbit polyclonal to TAB1
Tested applications
WB, ICC/IFmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
This antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of TAB1 (Human).
Positive control
3T3 cell lysate for Western blot.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.02% Sodium Azide.
Constituents: PBS.
Concentration
Concentration information loading...
Purity
Protein G purified
Primary antibody notes
This antibody can be used for the detection of TAB1 by Western blot at 0.5 to 1 µg/ml.
Clonality
Polyclonal
Isotype
IgG
Research areas
Immunology >> Innate Immunity >> TLR Signaling
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> MAPK Pathway
Applications
Show applications key
Our Abpromise guarantee covers the use of ab25878 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).
ICC/IF: Use a concentration of 1 µg/ml.
Target
Function
May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
Tissue specificity
Ubiquitous.
Sequence similarities
Contains 1 PP2C-like domain.
Post-translational
modifications
Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
Target information above from: UniProt accessionQ15750
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 2310012M03Rik antibody
- 3'-Tab1 antibody
- MAP3K7IP 1 antibody
see all
Database links
- Entrez Gene: 10454 Human
- Entrez Gene: 66513 Mouse
- Omim: 602615 Human
- SwissProt: Q15750 Human
- SwissProt: Q8CF89 Mouse
- Unigene: 507681 Human
- Unigene: 288245 Mouse
Anti-TAB1 antibody images:
Western blot - TAB1 antibody (ab25878)
Lane 1 : Anti-TAB1 antibody (ab25878) at 0.5 µg/ml
Lane 2 : Anti-TAB1 antibody (ab25878) at 1 µg/ml
Lane 3 : Anti-TAB1 antibody (ab25878) at 2 µg/ml
Lane 1 : 3T3 cell lysate 15ug
Lane 2 : 3T3 cell lysate 15ug
Lane 3 : 3T3 cell lysate 15ug
Predicted band size : 55 kDa
Immunocytochemistry/ Immunofluorescence - TAB1 antibody (ab25878)
ab25878 at 1µg/ml staining TAB1 in K562 cells By ICC/IF
References for Anti-TAB1 antibody (ab25878)
This product has been referenced in:
- Jin HS et al. cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation. Cancer Res 69:1782-91 (2009). WB; Human.Read more (PubMed: 19223549) »
See 1 publication for this product
Publishing research using ab25878? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"