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Anti-TADA3L antibody (ab42443)

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Overview

Product name

Anti-TADA3L antibody
See all TADA3L products (4) ...

Description

Rabbit polyclonal to TADA3L

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Dog

Immunogen

Synthetic peptide (Human). More details of the immunogen are not available.

Positive control

Jurkat cell lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Transcription >> Transcription Factors
Epigenetics and Nuclear Signaling >> Transcription >> Other factors

  • Western blot - TADA3L antibody (ab42443)Western blot - TADA3L antibody (ab42443) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab42443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 0.5 µg/mlDetects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).

Target

Relevance

TADA3L functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. TADA3L is also known as a coactivator for p53/TP53-dependent transcriptional activation. The PCAF complex is composed of a number of TBP-associated factors (TAFS), such as TAF5, TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and SPT3.

Cellular localization

Nuclear

Alternative names

  • ADA3 antibody
  • ADA3 homolog antibody
  • ADA3-like protein antibody
  • FLJ20221 antibody
  • FLJ21329 antibody
  • hADA3 antibody
  • Transcriptional adaptor 3 (NGG1 homolog yeast) like antibody
  • Transcriptional adaptor 3 like antibody
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Database links

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Anti-TADA3L antibody images:

  Western blot - TADA3L antibody (ab42443)

Western blot - TADA3L antibody (ab42443)

All lanes : Anti-TADA3L antibody (ab42443) at 0.5 µg/ml

Lane 1 : Markers
Lane 2 : Jurkat Cell Lysate


Predicted band size : 49 kDa
Observed band size : 49 kDa

References for Anti-TADA3L antibody (ab42443)

This product has been referenced in:

  • Guelman Set al. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol 29:1176-88 (2009). WB; Human.Read more (PubMed: 19103755) »

See 1 publication for this product

Publishing research using ab42443? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"