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Products:Epigenetics and Nuclear Signaling >> Transcription >> Polymerase associated factors >> Pol I Transcription
Overview
Product name
Anti-TAF1 48 antibody
See all TAF1 48 products (4) ...
Description
Mouse monoclonal to TAF1 48
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: MSDFSEELKG PVTDDEEVET SVLSGAGMHF PWLQTYVETV AIGGKRRKDF AQTTSACLSF IQEALLKHQW QQAAEYMYSY FQTLEDSDSY KRQAAPEIIW , corresponding to amino acids 1-101 of Human TAF1 48
MSDFSEELKG PVTDDEEVET SVLSGAGMHF PWLQTYVETV AIGGKRRKDF AQTTSACLSF IQEALLKHQW QQAAEYMYSY FQTLEDSDSY KRQAAPEIIW
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Epigenetics and Nuclear Signaling >> Transcription >> Polymerase associated factors >> Pol I Transcription
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Western blot - TAF1 48 antibody (ab56361)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab56361 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA binding protein (TBP) and three TBP associated factors (TAFs) specific for RNA polymerase I. This complex, also known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Cellular localization
Nuclear
Alternative names
- RAFI48 antibody
- TAFI48 antibody
- TATA box binding protein associated factor 1A antibody
see all
Database links
- Entrez Gene: 9015 Human
- Omim: 604903 Human
- SwissProt: Q15573 Human
- Unigene: 153088 Human
Anti-TAF1 48 antibody images:
Western blot - TAF1 48 antibody (ab56361)
Western blot against tagged recombinant protein immunogen using ab56361 TAF1 48 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
References for Anti-TAF1 48 antibody (ab56361)
ab56361 has not yet been referenced specifically in any publications.
Publishing research using ab56361? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"